From: Gout and subsequent erectile dysfunction: a population-based cohort study from England
Variable | Controls | Gout cases | Adjusteda HR | 95% CI | Absolute risk differenceb | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Rateb | 95% CI | N | Rateb | 95% CI | |||||||
Overall | 2429 | 80.2 | 77.1 | 83.5 | 1024 | 113.7 | 107.0 | 120.9 | 1.36 | 1.26 | 1.47 | 33.5 |
Age | ||||||||||||
≤ 34 | 32 | 16.3 | 11.5 | 23.0 | 23 | 33.6 | 22.4 | 50.6 | 1.24 | 0.67 | 2.29 | 17.3 |
35–44 | 329 | 45.7 | 41.1 | 51.0 | 139 | 62.4 | 52.8 | 73.6 | 1.11 | 0.89 | 1.37 | 16.6 |
45–54 | 925 | 87.1 | 81.6 | 92.9 | 391 | 126.8 | 114.8 | 140.0 | 1.30 | 1.15 | 1.47 | 39.7 |
55–64 | 1143 | 108.8 | 102.7 | 115.3 | 471 | 156.7 | 143.2 | 171.5 | 1.46 | 1.30 | 1.64 | 47.9 |
Smoking status | ||||||||||||
Never/ex-smokers | 1955 | 79.1 | 75.7 | 82.7 | 891 | 114.5 | 107.3 | 122.3 | 1.39 | 1.27 | 1.51 | 35.4 |
Current smoker | 474 | 84.9 | 77.6 | 92.9 | 133 | 108.5 | 91.6 | 128.7 | 1.23 | 1.01 | 1.51 | 23.6 |
Alcohol consumption | ||||||||||||
Never/ex-drinkers | 484 | 65.2 | 59.6 | 71.2 | 154 | 112.5 | 96.0 | 131.7 | 1.82 | 1.49 | 2.21 | 47.3 |
Current drinkers (1–9 units/week) | 992 | 76.7 | 72.0 | 81.6 | 321 | 98.4 | 88.2 | 109.8 | 1.27 | 1.11 | 1.44 | 21.7 |
Current drinkers (≥10 units/week) | 953 | 96.1 | 90.2 | 102.4 | 549 | 125.6 | 115.5 | 136.5 | 1.31 | 1.17 | 1.46 | 29.5 |
Body mass index | ||||||||||||
Normal | 589 | 73.3 | 67.6 | 79.5 | 116 | 91.0 | 75.9 | 109.2 | 1.27 | 1.03 | 1.56 | 17.7 |
Underweight | 10 | 37.5 | 20.2 | 69.7 | - | - | - | - | - | - | - | |
Overweight | 971 | 85.8 | 80.5 | 91.3 | 419 | 118.3 | 107.5 | 130.2 | 1.36 | 1.21 | 1.53 | 32.5 |
Obese | 581 | 92.5 | 85.3 | 100.3 | 399 | 114.4 | 103.7 | 126.2 | 1.28 | 1.12 | 1.46 | 21.9 |
Missing | 278 | 63.5 | 56.5 | 71.4 | 89 | 133.8 | 108.7 | 164.7 | 1.88 | 1.43 | 2.48 | 70.3 |
Comorbidities | ||||||||||||
Congestive heart disease | 199 | 78.2 | 68.1 | 89.9 | 123 | 110.7 | 92.7 | 132.1 | 1.34 | 1.06 | 1.70 | 32.4 |
Diabetes | 488 | 177.3 | 162.2 | 193.7 | 264 | 179.4 | 159.1 | 202.4 | 1.04 | 0.89 | 1.21 | 2.2 |
Hypertension | 737 | 94.9 | 88.3 | 102.0 | 486 | 118.0 | 107.9 | 128.9 | 1.24 | 1.10 | 1.39 | 23.1 |
Chronic renal disease | 51 | 44.4 | 33.8 | 58.5 | 52 | 60.3 | 45.9 | 79.1 | 1.34 | 0.90 | 1.99 | 15.8 |
Depression | 479 | 92.6 | 84.6 | 101.2 | 219 | 124.2 | 108.8 | 141.8 | 1.37 | 1.16 | 1.62 | 31.6 |