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Table 3 Absolute and relative rate of pharmacologically treated ED by patient characteristics and comorbidities

From: Gout and subsequent erectile dysfunction: a population-based cohort study from England

Variable Controls Gout cases Adjusteda HR 95% CI Absolute risk differenceb
N Rateb 95% CI N Rateb 95% CI   
Overall 2429 80.2 77.1 83.5 1024 113.7 107.0 120.9 1.36 1.26 1.47 33.5
Age
  ≤ 34 32 16.3 11.5 23.0 23 33.6 22.4 50.6 1.24 0.67 2.29 17.3
 35–44 329 45.7 41.1 51.0 139 62.4 52.8 73.6 1.11 0.89 1.37 16.6
 45–54 925 87.1 81.6 92.9 391 126.8 114.8 140.0 1.30 1.15 1.47 39.7
 55–64 1143 108.8 102.7 115.3 471 156.7 143.2 171.5 1.46 1.30 1.64 47.9
Smoking status
 Never/ex-smokers 1955 79.1 75.7 82.7 891 114.5 107.3 122.3 1.39 1.27 1.51 35.4
 Current smoker 474 84.9 77.6 92.9 133 108.5 91.6 128.7 1.23 1.01 1.51 23.6
Alcohol consumption
 Never/ex-drinkers 484 65.2 59.6 71.2 154 112.5 96.0 131.7 1.82 1.49 2.21 47.3
 Current drinkers (1–9 units/week) 992 76.7 72.0 81.6 321 98.4 88.2 109.8 1.27 1.11 1.44 21.7
 Current drinkers (≥10 units/week) 953 96.1 90.2 102.4 549 125.6 115.5 136.5 1.31 1.17 1.46 29.5
Body mass index
 Normal 589 73.3 67.6 79.5 116 91.0 75.9 109.2 1.27 1.03 1.56 17.7
 Underweight 10 37.5 20.2 69.7   - - - - - - -
 Overweight 971 85.8 80.5 91.3 419 118.3 107.5 130.2 1.36 1.21 1.53 32.5
 Obese 581 92.5 85.3 100.3 399 114.4 103.7 126.2 1.28 1.12 1.46 21.9
 Missing 278 63.5 56.5 71.4 89 133.8 108.7 164.7 1.88 1.43 2.48 70.3
Comorbidities
 Congestive heart disease 199 78.2 68.1 89.9 123 110.7 92.7 132.1 1.34 1.06 1.70 32.4
 Diabetes 488 177.3 162.2 193.7 264 179.4 159.1 202.4 1.04 0.89 1.21 2.2
 Hypertension 737 94.9 88.3 102.0 486 118.0 107.9 128.9 1.24 1.10 1.39 23.1
 Chronic renal disease 51 44.4 33.8 58.5 52 60.3 45.9 79.1 1.34 0.90 1.99 15.8
 Depression 479 92.6 84.6 101.2 219 124.2 108.8 141.8 1.37 1.16 1.62 31.6
  1. ED erectile dysfunction, HR hazard ratio, CI confidence interval
  2. aMutually adjusted unless stratified
  3. bPer 10,000 person-years