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Table 3 Absolute and relative rate of pharmacologically treated ED by patient characteristics and comorbidities

From: Gout and subsequent erectile dysfunction: a population-based cohort study from England

Variable

Controls

Gout cases

Adjusteda HR

95% CI

Absolute risk differenceb

N

Rateb

95% CI

N

Rateb

95% CI

  

Overall

2429

80.2

77.1

83.5

1024

113.7

107.0

120.9

1.36

1.26

1.47

33.5

Age

  ≤ 34

32

16.3

11.5

23.0

23

33.6

22.4

50.6

1.24

0.67

2.29

17.3

 35–44

329

45.7

41.1

51.0

139

62.4

52.8

73.6

1.11

0.89

1.37

16.6

 45–54

925

87.1

81.6

92.9

391

126.8

114.8

140.0

1.30

1.15

1.47

39.7

 55–64

1143

108.8

102.7

115.3

471

156.7

143.2

171.5

1.46

1.30

1.64

47.9

Smoking status

 Never/ex-smokers

1955

79.1

75.7

82.7

891

114.5

107.3

122.3

1.39

1.27

1.51

35.4

 Current smoker

474

84.9

77.6

92.9

133

108.5

91.6

128.7

1.23

1.01

1.51

23.6

Alcohol consumption

 Never/ex-drinkers

484

65.2

59.6

71.2

154

112.5

96.0

131.7

1.82

1.49

2.21

47.3

 Current drinkers (1–9 units/week)

992

76.7

72.0

81.6

321

98.4

88.2

109.8

1.27

1.11

1.44

21.7

 Current drinkers (≥10 units/week)

953

96.1

90.2

102.4

549

125.6

115.5

136.5

1.31

1.17

1.46

29.5

Body mass index

 Normal

589

73.3

67.6

79.5

116

91.0

75.9

109.2

1.27

1.03

1.56

17.7

 Underweight

10

37.5

20.2

69.7

 

-

-

-

-

-

-

-

 Overweight

971

85.8

80.5

91.3

419

118.3

107.5

130.2

1.36

1.21

1.53

32.5

 Obese

581

92.5

85.3

100.3

399

114.4

103.7

126.2

1.28

1.12

1.46

21.9

 Missing

278

63.5

56.5

71.4

89

133.8

108.7

164.7

1.88

1.43

2.48

70.3

Comorbidities

 Congestive heart disease

199

78.2

68.1

89.9

123

110.7

92.7

132.1

1.34

1.06

1.70

32.4

 Diabetes

488

177.3

162.2

193.7

264

179.4

159.1

202.4

1.04

0.89

1.21

2.2

 Hypertension

737

94.9

88.3

102.0

486

118.0

107.9

128.9

1.24

1.10

1.39

23.1

 Chronic renal disease

51

44.4

33.8

58.5

52

60.3

45.9

79.1

1.34

0.90

1.99

15.8

 Depression

479

92.6

84.6

101.2

219

124.2

108.8

141.8

1.37

1.16

1.62

31.6

  1. ED erectile dysfunction, HR hazard ratio, CI confidence interval
  2. aMutually adjusted unless stratified
  3. bPer 10,000 person-years