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Table 4 Absolute and relative rate of ED among those ever prescribed urate-lowering therapy (ULT)

From: Gout and subsequent erectile dysfunction: a population-based cohort study from England

  1-year landmark analysis Total patients = 9322 ULT exposed = 1249 3-year landmark analysis Total patients = 8650 ULT exposed = 1787
Gout cases ED events Absolute rateb (95% CI) Adjusted HR (95% CI)a ED events Absolute rateb (95% CI) Adjusted HR (95% CI)a
For overall ED reporting
 Not treated 1364 194.8 (184.7–205.4) 1.00 797 196.9 (184.9–209.6) 1.00
 Treated with ULT 252 237.1 (209.6–268.3) 1.14 (0.99–1.30) 294 229.1 (204.4–256.9) 1.07 (0.94–1.22)
Pharmacologically treated ED
 Not treated 797 113.8 (106.2–122.0) 1.00 548 110.3 (101.5–120) 1.00
 Treated with ULT 141 132.8 (112.5–156.5) 1.12 (0.93–1.34) 161 125.5 (107.5–146.4) 1.08 (0.90–1.29)
  1. ED erectile dysfunction, CI confidence interval, HR hazard ratio
  2. aAdjusted for age, BMI, smoking status, alcohol consumption, ischemic heart disease, chronic renal disease, depression, hypertension and diabetes
  3. bPer 10,000 person-years