Skip to main content

Table 4 Absolute and relative rate of ED among those ever prescribed urate-lowering therapy (ULT)

From: Gout and subsequent erectile dysfunction: a population-based cohort study from England

 

1-year landmark analysis

Total patients = 9322

ULT exposed = 1249

3-year landmark analysis

Total patients = 8650

ULT exposed = 1787

Gout cases

ED events

Absolute rateb (95% CI)

Adjusted HR (95% CI)a

ED events

Absolute rateb (95% CI)

Adjusted HR (95% CI)a

For overall ED reporting

 Not treated

1364

194.8 (184.7–205.4)

1.00

797

196.9 (184.9–209.6)

1.00

 Treated with ULT

252

237.1 (209.6–268.3)

1.14 (0.99–1.30)

294

229.1 (204.4–256.9)

1.07 (0.94–1.22)

Pharmacologically treated ED

 Not treated

797

113.8 (106.2–122.0)

1.00

548

110.3 (101.5–120)

1.00

 Treated with ULT

141

132.8 (112.5–156.5)

1.12 (0.93–1.34)

161

125.5 (107.5–146.4)

1.08 (0.90–1.29)

  1. ED erectile dysfunction, CI confidence interval, HR hazard ratio
  2. aAdjusted for age, BMI, smoking status, alcohol consumption, ischemic heart disease, chronic renal disease, depression, hypertension and diabetes
  3. bPer 10,000 person-years