RHC referral rate, % | Missed diagnoses, % | Sensitivity % | Specificity % | PPV % | NPV % | ||
---|---|---|---|---|---|---|---|
PAH vs no PH patients | DETECT algorithm (95% CI) | 51/63, 80.9% - | 0/35, 0% - | 100% (90.1–100) | 42.9% (26.5–60.9) | 68.6% (55.0–79.7) | 100% (75.7–100) |
ESC/ERS guidelines (95% CI) | 36/63, 57.1% - | 3/35, 8.5% - | 91.4% (77.6–97.0) | 85.7% (68.5–94.3) | 88.9% (74.7–95.6) | 88.9% (71.9–96.1) | |
Patients with mPAP ≥21 vs mPAP <21mmg | DETECT algorithm (95% CI) | 51/63, 80.9% - | 3/49, 6.1% - | 93.9% (83.5–97.9) | 64.3% (38.8–83.7) | 90.2% (79.0–95.7) | 75.0% (46.8–91.1) |
ESC/ERS guidelines (95% CI) | 36/63, 57.1% - | 15/49, 30.6% - | 69.4% (55.5–80.5) | 85.7% (60.1–96.0) | 94.4% (81.9–98.5) | 44.4% (27.6–62.7) | |
PH vs no PH patients | DETECT algorithm (95% CI) | 68/83, 81.9% - | 1/52, 1.9% - | 98.1% (89.9–99.7) | 45.2% (29.2–62.2) | 75.0% (63.6–83.8) | 93.3% (70.2–98.8) |
ESC/ERS guidelines (95% CI) | 46/83, 55.4% - | 10/52, 19.2% - | 80.8% (68.1–89.2) | 87.1% (71.1–94.9) | 91.3% (79.7–96.6) | 73.0% (57.0–84.6) |