Approaches for DAS28-CRP adjustment | Description |
---|---|
1. No adjustment | No inclusion of any DAS28-CRP values. |
2. Most recent prior measurement | Adjust for most recent DAS28-CRP value prior to start of treatment. |
3. Most recent after measurement | Adjust for most recent DAS28-CRP value after start of treatment. |
4. Arithmetic mean | Adjust for the arithmetic mean of the two nearest DAS28-CRP measurements. |
5. Nearest measurement | Adjust for nearest DAS28-CRP measurement. |
6. Weighted mean | Adjust for the weighted mean of the two nearest DAS28-CRP measurements, accounting for proximity. |
7. Restricted to within 4 months | Only include subjects with DAS28-CRP within 4 months of start of treatment, prior or post. |
8. Restricted to within 2 months | Only include subjects with DAS28-CRP within 2 months of start of treatment, prior or post. |
9. Restricted to within 10 months prior | Only include subjects with DAS28-CRP within 10 months prior to start of treatment. |
10. Restricted to within 8 months prior | Only include subjects with DAS28-CRP within 8 months prior to start of treatment. |
11. Restricted to within 6 months prior | Only include subjects with DAS28-CRP within 6 months prior to start of treatment. |
12. Restricted to within 4 months prior | Only include subjects with DAS28-CRP within 4 months prior to start of treatment. |
13. Restricted to within 2 months prior | Only include subjects with DAS28-CRP within 2 months prior to start of treatment. |