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Table 3 Association of family history manifestations with the fulfilment of ASAS axSpA criteria in the SPACE cohort and DESIR cohorts

From: Is the current ASAS expert definition of a positive family history useful in identifying axial spondyloarthritis? Results from the SPACE and DESIR cohorts

 

Fulfilment of ASAS axSpA criteria

SPACE

DESIR

OR (95% CI)

P- value

OR (95% CI)

P- value

Any PFH

2.1 (1.4-3.1)

<0.001

1.3 (1.0-1.9)

0.091

AS

3.3 (2.0-5.3)

<0.001

2.1 (1.3-3.3)

<0.001

AAU

7.4 (2.5-21.7)

<0.001

5.0 (1.5-16.7)

0.009

ReA

0.6 (0.2-1.9)

0.421

0.3 (0.05-1.5)

0.132

IBD

1.1 (0.5-2.2)

0.798

0.8 (0.4-1.6)

0.521

Psoriasis

1.2 (0.8-2.0)

0.388

1.2 (0.8-1.8)

0.464

  1. Any PFH, any family history manifestation in first- or second-degree relatives; AS ankylosing spondylitis, AAU acute anterior uveitis, ReA reactive arthritis, IBD inflammatory bowel disease, OR odds ratio, 95% CI 95% confidence interval