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Table 3 Association of family history manifestations with the fulfilment of ASAS axSpA criteria in the SPACE cohort and DESIR cohorts

From: Is the current ASAS expert definition of a positive family history useful in identifying axial spondyloarthritis? Results from the SPACE and DESIR cohorts

  Fulfilment of ASAS axSpA criteria
SPACE DESIR
OR (95% CI) P- value OR (95% CI) P- value
Any PFH 2.1 (1.4-3.1) <0.001 1.3 (1.0-1.9) 0.091
AS 3.3 (2.0-5.3) <0.001 2.1 (1.3-3.3) <0.001
AAU 7.4 (2.5-21.7) <0.001 5.0 (1.5-16.7) 0.009
ReA 0.6 (0.2-1.9) 0.421 0.3 (0.05-1.5) 0.132
IBD 1.1 (0.5-2.2) 0.798 0.8 (0.4-1.6) 0.521
Psoriasis 1.2 (0.8-2.0) 0.388 1.2 (0.8-1.8) 0.464
  1. Any PFH, any family history manifestation in first- or second-degree relatives; AS ankylosing spondylitis, AAU acute anterior uveitis, ReA reactive arthritis, IBD inflammatory bowel disease, OR odds ratio, 95% CI 95% confidence interval