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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles

Fig. 5

Two biologically relevant proteins, matrix metalloproteinase-1 (MMP1) and S100 calcium binding protein A13 (S100-A13), that were identified by proteomic analysis as differentially abundant in the SF of non-responders between Stages I (SI) and II (SII) of the ACI procedure were validated by ELISA. a The differential abundance as measured by label-free mass-spectrometry and by biochemical ELISA. MMP1 was measured by ELISA in the SF of (b) non-responders (NR) and (c) responders (R) to ACI at cartilage harvest (Stage I; S1) and chondrocyte implantation (Stage II; S2). S100-A13 was measured by ELISA in the SF of non-responders (d) and responders (e) to ACI

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Arthritis Research & Therapy

ISSN: 1478-6362

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