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Table 3 Proteins that are differentially expressed with a ≥2.0-fold-change in the synovial fluid collected at Stage I compared to Stage II of the ACI procedure in clinical responders

From: Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles

Protein

Fold change

Description

Accession

Heat shock protein 75 kDa, mitochondrial

Q12931

–470.0

Microtubule-associated protein 1B

P46821

–17.2

Adenosylhomocysteinase

P23526

–3.7

Complement factor H-related protein 3

Q02985

–2.8

Mannose-1-phosphate guanyltransferase beta

Q9Y5P6

–2.7

Peroxiredoxin-4

Q13162

–2.5

Oxysterol-binding protein 1

P22059

–2.4

Protein canopy homolog 3

Q9BT09

–2.1

Spermatid perinuclear RNA-binding protein

Q96SI9

–2.0

Ferritin light chain

P02792

2.2

Secreted phosphoprotein 24

Q13103

2.2

Chondroitin sulfate proteoglycan 4

Q6UVK1

2.3

Collagen alpha-2(I) chain

P08123

2.3

Collagen alpha-1(V) chain

P20908

2.5

26S protease regulatory subunit 6A

P17980

2.7

Collagen alpha-2(V) chain

P05997

2.9

Collagen alpha-1(I) chain

P02452

3.3

Spectrin alpha chain, erythrocytic 1

P02549

4.1

Histidine triad nucleotide-binding protein 1

P49773

4.2

Platelet factor 4

P02776

4.2

Alpha-1-acid glycoprotein 2

P19652

4.3

Protein 4.1

P11171

4.3

Periostin

Q15063

4.5

26S proteasome non-ATPase regulatory subunit 13

Q9UNM6

4.6

  1. Positive numbers denote an increase in the protein at Stage II, negative numbers denote a decrease in the protein at Stage II