Variable | Change with prucalopridea | Change without treatmenta | Effect sizea | Ratingb | p |
---|---|---|---|---|---|
Likert GERD | -0.678 ± 0.108 | -0.001 ± 0.114 | -0.677 | NA | 7.8*10-5 |
Likert constipation | -1.282 ± 0.155 | 0.135 ± 0.158 | -1.417 | NA | 2.01*10-7 |
UCLA GIT 2.0 | -0.147 ± 0.061 | 0.021 ± 0.063 | -0.168 | Same | 0.047 |
UCLA GIT 2.0 Constipation | -0.672 ± 0.112 | 0.086 ± 0.115 | -0.758 | Much better | 5.4*10-5 |
UCLA GIT 2.0 Subscales | |||||
 Reflux  Bloating  Fecal soilage  Diarrhea  Social activities  Emotional wellbeing | -0.409 ± 0.094 -0.418 ± 0.088 -0.097 ± 0.133 0.367 ± 0.093 -0.106 ± 0.11 -0.214 ± 0.093 | 0.01 ± 0.096 -0.084 ± 0.09 0.074 ± 0.141 0.089 ± 0.097 -0.006 ± 0.112 0.017 ± 0.093 | -0.419 -0.334 -0.171 0.277 -0.1 -0.231 | Better Better Same Worse Better Same | 0.003 0.011 0.38 0.053 0.503 0.051 |