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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus

Fig. 1

Vascular endothelial growth factor (VEGF) pathway perturbation after topical immunotherapy. Network representation of VEGF genes according to the differential gene expression after treatment with common topical immunotherapies: imiquimod (a), betamethasone valerate (b), diphencyprone (c) and pimecrolimus (d). Genes are represented as nodes and are connected by edges according to experimental or computational evidence of interaction between their encoded proteins. The diameter of each node is proportional to the significance of differential expression, with significant genes (P < 0.05) in red and non-significant genes (P ≥ 0.05) in blue

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