Pre-symptomatic individuals (n = 547) | Controls (n = 1641) | OR (95% CI) | Pre-symptomatic women (n = 372) | Control women (n = 1116) | OR (95% CI) | Pre-symptomatic men (n = 175) | Control men (n = 525) | OR (95% CI) | |
---|---|---|---|---|---|---|---|---|---|
Plasma glucose, 0 hours (mmol/L)a | 5.40 (5.05–5.84) (n = 513) | 5.40 (5.00–5.80) (n = 1543) | 1.11 (1.00–1.22) | 5.40 (5.00–5.80) (n = 349) | 5.38 (5.00–5.80) (n = 1052) | 1.05 (0.92–1.21) | 5.50 (5.10–6.00) (n = 164) | 5.50 (5.10–5.90) (n = 491) | 1.18 (1.01–1.37) |
Plasma glucose, 2 hours (mmol/L)a | 6.60 (5.70–7.30) (n = 470) | 6.70 (5.90–7.60) (n = 1473) | 0.94 (0.88–1.01) | 6.67 (5.80–7.4) (n = 327) | 6.80 (6.00–7.70) (n = 1005) | 0.92 (0.85–1.00) | 6.38 (5.40–7.10) (n = 143) | 6.40 (5.40–7.40) (n = 468) | 0.98 (0.87–1.10) |
Systolic blood pressure (mmHg)a | 128 (118–140) (n = 542) | 129 (118–140) (n = 1637) | 1.00 (0.99–1.01) | 128 (115–140) (n = 368) | 127 (118–140) (n = 1113) | 1.00 (0.99–1.01) | 128 (120–139) (n = 174) | 130 (120–140) (n = 524) | 1.00 (0.99–1.01) |
Diastolic blood pressure (mmHg)a | 80 (70–88) (n = 542) | 80 (72–86) (n = 1635) | 1.00 (0.99–1.01) | 79 (70–87) (n = 368) | 80 (70–85) (n = 1112) | 1.00 (0.98–1.01) | 80 (75–90) (n = 174) | 80 (75–90) (n = 523) | 1.00 (0.99–1.02) |
Total cholesterol (mmol/L)a | 5.74 (5.01–6.49) (n = 535) | 5.70 (4.93–6.50) (n = 1619) | 1.04 (0.96–1.14) | 5.74 (5.01–6.57) (n = 361) | 5.71 (4.94–6.57) (n = 1103) | 1.04 (0.93–1.16) | 5.76 (5.03–6.46) (n = 174) | 5.70 (4.90–6.48) (n = 516) | 1.06 (0.91–1.23) |
Triglycerides (mmol/L)a | 1.20 (0.89–1.60) (n = 453) | 1.18 (0.84–1.70) (n = 1390) | 0.95 (0.82–1.10) | 1.16 (0.83–1.56) (n = 312) | 1.14 (0.80–1.60) (n = 960) | 0.95 (0.79–1.15) | 1.29 (0.96–1.70) (n = 141) | 1.36 (0.95–1.87) (n = 430) | 0.94 (0.75–1.18) |
HDL-cholesterol (mmol/L)a | 1.26 (1.04–1.51) (n = 152) | 1.32 (1.08–1.60) (n = 517) | 0.81 (0.46–1.46) | 1.30 (1.10–1.54) (n = 100) | 1.40 (1.19–1.66) (n = 341) | 0.65 (0.32–1.34) | 1.19 (0.92–1.40) (n = 52) | 1.14 (0.96–1.39) (n = 176) | 1.60 (0.49–5.22) |
LDL-cholesterol (mmol/L)a | 4.13 (3.15–4.76) (n = 143) | 4.07 (3.19–4.79) (n = 474) | 1.12 (0.90–1.41) | 4.08 (3.13–4.61) (n = 96) | 4.02 (3.20–4.79) (n = 320) | 1.06 (0.80–1.40) | 4.28 (3.60–5.06) (n = 47) | 4.14 (3.17–4.84) (n = 154) | 1.25 (0.85–1.83) |
ApoA1 (g/L)a | 1.39 (1.23–1.57) (n = 453) | 1.42 (1.28–1.59) (n = 1389) | 0.50 (0.31–0.80) | 1.46 (1.28–1.60) (n = 304) | 1.47 (1.33–1.63) (n = 943) | 0.49 (0.28–0.85) | 1.31 (1.15–1.46) (n = 149) | 1.32 (1.20–1.47) (n = 446) | 0.53 (0.22–1.30) |
ApoB (g/L)a | 1.05 (0.86–1.24) (n = 453) | 1.02 (0.86–1.21) (n = 1390) | 1.50 (0.96–2.36) | 1.02 (0.84–1.22) (n = 304) | 1.00 (0.84–1.17) (n = 944) | 1.66 (0.95–2.91) | 1.11 (0.93–1.28) (n = 149) | 1.09 (0.91–1.27) (n = 446) | 1.24 (0.58–2.67) |
Ratio ApoB/ApoA1 | 0.75 (0.60–0.93) (n = 453) | 0.71 (0.58–0.88) (n = 1389) | 2.05 (1.28–3.29) | 0.70 (0.57–0.87) (n = 304) | 0.67 (0.56–0.82) (n = 943) | 2.25 (1.25–4.06) | 0.86 (0.69–1.03) (n = 149) | 0.82 (0.67–1.00) (n = 446) | 1.74 (0.79–3.83) |