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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis

Fig. 5

Blockade of connective tissue growth factor (CTGF) reduces the number of pSmad-positive cells. a Representative results of immunostaining for pSmad2. Scale bar 50 μm. b The pSmad2-positive cells were counted in five random high-power fields using a light microscope. The mean score was used for analysis. Each graph represents mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001. Ang II angiotensin II, KO knockout

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