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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Abatacept reduces synovial regulatory T-cell expression in patients with psoriatic arthritis

Fig. 2

Immunohistological comparison of the expression of CD4+ and forkhead box protein transcription factor 3-positive (FOXP3+) T cells (magnification × 10) in the synovial tissue prior to and at 6 months after abatacept treatment (patient #6). Baseline images show focal infiltration of CD4+ T cells (a) and FOXP3+ T cells (b) in a villus. Decrease in CD4 expression and significant reduction in the number of FOXP3+ T cells are shown (c and d, respectively)

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