From: Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout
NZ European | NZ Polynesian | ARIC | FHS | |||||
---|---|---|---|---|---|---|---|---|
Control | Gout | Control | Gout | NU | HU | NU | HU | |
Number | 374 | 665 | 916 | 837 | 3443 | 690 | 2364 | 395 |
Male sex, n (%) | 252 (67.4) | 541 (81.3) | 409 (44.8) | 695 (83.0) | 1255 (36.4) | 581 (84.2) | 878 (37.1) | 376 (95.19) |
Age, years | 53.15 ± 17.02 | 63.13 ± 13.39 | 42.97 ± 15.08 | 51.75 ± 13.01 | 53.23 ± 5.49 | 53.49 ± 5.61 | 39.44 ± 8.72 | 39.38 ± 8.26 |
BMI, kg/m2 | 27.58 ± 6.11 (98.4)a | 30.36 ± 5.56 (98.2) | 33.03 ± 7.53 (98.4) | 36.38 ± 8.25 (97.5) | 25.41 ± 4.05 (100) | 28.34 ± 4.16 (100) | 25.71 ± 4.92 (100) | 29.56 ± 4.80 (100) |
Serum urate, mmol/L | 0.335 ± 0.102 (93.6) | 0.388 ± 0.113 (69.0) | 0.375 ± 0.088 (83.2) | 0.433 ± 0.115 (82.8) | 0.305 ± 0.058 (100) | 0.449 ± 0.041 (100) | 0.281 ± 0.065 (100) | 0.450 ± 0.040 (100) |
Number of alcohol consumers, n (%) | 277 (74.1) | 463 (69.62) | 373 (40.7) | 365 (43.6) | 1568 (45.5) | 394 (57.1) | 1881 (79.6) | 328 (83.0) |
Alcohol consumption, g/week | 75.48 ± 96.36 (100) | 80.77 ± 110.96 (100) | 42.61 ± 91.41 (100) | 54.91 ± 121.23 (100) | 21.42 ± 42.94 (100) | 36.56 ± 60.63 (100) | 59.66 ± 79.27 (100) | 99.35 ± 110.71 (100) |
Triglycerides, mmol/L | 1.74 ± 1.00 (93.3) | 2.23 ± 1.47 (69.0) | 2.02 ± 1.29 (83.2) | 2.42 ± 1.67 (82.8) | 1.26 ± 0.75 (99.9) | 1.87 ± 1.07 (100) | 2.58 ± 1.64 (100) | 4.34 ± 3.82 (100) |
eGFR, ml/min/1.73 m2 | 74.77 ± 16.85 (93.3) | 62.41 ± 19.86 (68.1) | 75.96 ± 16.73 (82.7) | 64.37 ± 21.17 (81.6) | 66.74 ± 9.65 (100) | 65.83 ± 9.11 (100) | 96.40 ± 16.94 (100) | 93.89 ± 16.91 (100) |