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Table 4 Alcohol intake and gout association results in genotype-stratified groups in people of Polynesian ancestry for GCKR

From: Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout

  No alcohol intake (n = 1007) Any alcohol intake (n = 732)  
Adjusted OR (95% CI) P value Adjusted OR (95% CI) P value P Difference
All T- 1 1 1.73 (1.21–2.46) 0.002  
  T+ 1.92 (1.41–2.62) 3.18 × 10−5 2.07 (1.47–2.92) 2.91 × 10−5 0.25
Beer T− 1 1 1.60 (1.10–2.32) 0.013  
  T+ 1.70 (1.28–2.25) 2 × 10−4 2.17 (1.50–3.13) 3.79 × 10−5 0.13
Nonbeer T− 1 1 1.68 (1.09–2.59) 0.020  
  T+ 1.78 (1.37–2.32) 1.95 × 10−5 1.81 (1.22–2.67) 0.003 0.66
  1. Associations are adjusted for age, sex, body mass index, STRUCTURE ancestry estimates, and ancestry class (Western vs. Eastern Polynesian vs. mixed Western/Eastern Polynesians). P Difference is that between genotype groups in the alcohol-exposed subset