Table 2 Crude response rates at 1 year of treatment with a first TNF inhibitor after stratification for different BMI categories
From: Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis
BMI category | |||||
|---|---|---|---|---|---|
Outcome | n = 531 | Normal n = 282 | Overweight n = 178 | Obese n = 71 | p |
ASAS40 | 494 | 44% | 34% | 29% | 0.02 |
ASAS40 TNFi other than INF | 383 | 45% | 34% | 24% | 0.008 |
ASAS40 TNFi: INF | 111 | 42% | 36% | 44% | 0.83 |
ASAS partial remission | 531 | 39% | 24% | 17% | <0.001 |
BASDAI-50 | 488 | 48% | 40% | 33% | 0.06 |
ASDAS improvement ≥1.1 | 423 | 59% | 46% | 37% | 0.003 |
ASDAS <2.1 | 468 | 56% | 41% | 25% | <0.001 |
ASDAS improvement ≥2 | 423 | 25% | 25% | 13% | 0.14 |
ASDAS <1.3 | 468 | 29% | 15% | 10% | <0.001 |