Fig. 5
From: Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody
Evaluation of ocular inflammation in experimental autoimmune uveitis (EAU) mice treated with Dow2 or rat IgG isotype control. At 21 days postimmunization, the retinas of EAU mice were examined by FA, hematoxylin and eosin (H&E) staining of paraffin-embedded sections, and immunohistochemistry for CD3+ cells. Representative images are shown for (a) FA, (b) H&E staining of retinal sections (scale bar = 20 μm), and (c) immunohistochemistry of retinal sections (scale bar = 20 μm). Left panels present bright field images and right panels present fluorescence images stained for CD3 (red) and with DAPI (blue). For FA, representative data from three independent experiments with similar results are shown. For H&E staining and immunohistochemistry, n = 8 eyes per group