Fig. 8
From: Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody
Effect of systemic Dow2 administration on peripheral T cells in experimental autoimmune uveitis (EAU) mice. Subpopulations of peripheral T cells were characterized by flow cytometry following splenocyte collection from normal mice, Dow2-treated EAU mice, and rat IgG-treated EAU mice. Splenocytes were analyzed for expression of (a) CD44/CD62L, (b) CD4/Foxp3, and (c) CD4 and CD8. In (c), percentages indicate the proportion of CD4+ or CD8+ cells. Representative data from four independent FACS experiments with similar results are shown