Fig. 1

Heat map for 58 IgG autoantibody specificities analyzed on a planar array. Serum samples were obtained from normal controls (NC), first-degree relatives of patients (FDR), and patients with incomplete lupus (ILE), or systemic lupus (SLE). The normalized fluorescent intensity values were used to generate the heat map. Clustering algorithms were used to detect autoantibodies that grouped together for the tested samples. Red color indicates reactivities that are above the mean of all samples, green corresponds to values below that mean and values close to the mean are black. From Li et al., Clin Exp Immunol 2007 [52] with permission