Skip to main content

Table 2 GO enrichment analysis results of differentially methylated genes between AS patients and healthy controls

From: Genome-wide DNA methylation profile analysis identifies differentially methylated loci associated with ankylosis spondylitis

GO ID

Description

Genes

P value

GO:0002504

Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPB1, HLA-DQA1, HLA-DQB1

1.11 × 10–5

GO:0042605

Peptide antigen binding

DHCR24, HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1, HLA-H, MAML1, SLC7A5

5.14 × 10–6

GO:0042613

MHC class II protein complex

HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRB1

7.97 × 10–6

GO:0071556

Integral to lumenal side of endoplasmic reticulum membrane

CALR, HLA-A, HLA-B, HLA-C, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRB1

8.79 × 10–5

  1. GO Gene Ontology, AS ankylosing spondylitis