Fig. 2From: High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathwayMeasurement of reactive oxygen species (ROS) generation and cell proliferation of nucleus pulposus (NP) cells from scaffold culture. a 20% deformation compression increased ROS generation, which was reversed by treatment with the ROS scavenger NAC. b NP cells from the 20% deformation group had a decreased cell proliferation potency compared with those from the 2% deformation group. Data are expressed as the mean ± SD (n = 3). *Indicates a significant difference (p < 0.05) between two groups; #indicates a significant difference (p < 0.05) compared with the control groupBack to article page