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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway

Fig. 2

Measurement of reactive oxygen species (ROS) generation and cell proliferation of nucleus pulposus (NP) cells from scaffold culture. a 20% deformation compression increased ROS generation, which was reversed by treatment with the ROS scavenger NAC. b NP cells from the 20% deformation group had a decreased cell proliferation potency compared with those from the 2% deformation group. Data are expressed as the mean ± SD (n = 3). *Indicates a significant difference (p < 0.05) between two groups; #indicates a significant difference (p < 0.05) compared with the control group

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