Skip to main content


Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway

Fig. 5

Analysis of p38 MAPK activity from nucleus pulposus (NP) cells in scaffold culture. 20% deformation compression significantly increased p38 MAPK activity and treatment with the ROS scavenger NAC had no significant effect on 20% deformation compression-induced p38 MAPK pathway activation. Data are expressed as the mean ± SD (n = 3). *Indicates a significant difference (p < 0.05) between two groups; #indicates a significant difference (p < 0.05) compared with the control group

Back to article page