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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study

Fig. 3

Validation of the scoring system in the second set of 228 patients from five hospitals. There were no significant differences between the prior rates of good response or non-response in the tocilizumab (TCZ) and TNF inhibitor (TNF-i) groups. Patients with a score of 2 or more points (48.1% of the TCZ group and 49.5% of the TNF-i group) had a significantly higher rate of good response and a lower rate of non-response to TCZ treatment compared with TNF-i treatment. This tendency became remarkable in patients with 3 or more points (24.8% of the TCZ group and 29.3% of the TNF-i group). In contrast, if the score was 1 or less (51.9% of the TCZ group and 50.5% of the TNF-i group), a TNF-i may be preferable because a higher rate of good response and a lower rate of non-response were observed in the TNF-i group compared with the TCZ group, although these differences were not significant: *p < 0.05, **p < 0.01. N.S. not significant

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Arthritis Research & Therapy

ISSN: 1478-6362

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