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Table 2 Baseline characteristics of study participants
| MPC + HA (n = 11) | HA alone (n = 6) | p* | |
|---|---|---|---|
| Age, years | 26.0 (3.6) | 26.9 (10.3) | 0.85 |
| Females, number (%) | 3 (27) | 2 (33) | 0.79 |
| Body mass index, kg/m2 | 25.1 (3.1) | 25.1 (4.6) | 1.00 |
| Interval between ACL injury and reconstruction, days | 76.5 (54.3) | 61.7 (34.8) | 0.56 |
| Interval between ACL reconstruction and intra-articular injection, days | 48.5 (14.0) | 47.8 (8.3) | 0.92 |
| KOOS | |||
| Pain | 69.1 (11.7) | 84.2 (11.9) | 0.02 |
| Symptoms | 59.7 (10.8) | 83.9 (11.7) | <0.001 |
| Activities of daily living | 82.1 (11.0) | 92.8 (6.4) | 0.047 |
| Sport and recreation function | 29.7 (17.6) | 40.0 (14.1) | 0.47 |
| Knee-related quality of life | 40.9 (19.8) | 50.0 (16.8) | 0.36 |
| SF-36 physical component score | 41.3 (4.7) | 45.9 (5.8) | 0.11 |
| Physical functioning | 41.0 (6.2) | 43.7 (1.7) | 0.31 |
| Role limitation: physical | 40.0 (7.0) | 42.6 (8.1) | 0.51 |
| Bodily pain | 42.3 (8.6) | 53.5 (5.4) | 0.01 |
| General health perception | 55.2 (6.6) | 55.4 (7.9) | 0.95 |
| Joint space width, mm | |||
| Medial tibiofemoral compartment | 4.36 (0.55) | 4.97 (0.63) | 0.06 |
| Lateral tibiofemoral compartment | 5.38 (0.62) | 5.67 (0.52) | 0.36 |
| Knee structure measured from MRI | |||
| Medial tibial cartilage volume, mm3 | 2456 (397) | 2627 (476) | 0.44 |
| Lateral tibial cartilage volume, mm3 | 3291 (401) | 3548 (847) | 0.51 |
| Medial tibial plateau bone area, mm2 | 2299 (337) | 2187 (182) | 0.46 |
| Lateral tibial plateau bone area, mm2 | 1472 (202) | 1415 (193) | 0.58 |
