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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Fig. 1

Immunological profiles of MRL/lpr mice at 10 and 14 weeks of age. After the mice were sacrificed, the spleens, axillary lymph nodes, femurs, and kidneys were removed and analyzed. a Weight of spleen and axillary lymph nodes. b Number of cellular subsets of spleen, axillary lymph nodes, and bone marrow from one femur. c Serum concentration of immunoglobulin subsets and anti-dsDNA antibody titer. d Histopathological analysis of glomerulonephritis at 10 and 14 weeks of age. Values expressed as median with quartile range. Statistical analysis performed using the nonparametric Mann–Whitney test

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