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Table 1 Baseline characteristics by radiographic progression at 1 year and bone mineral density loss after 3 months

From: Decrease in bone mineral density during three months after diagnosis of early rheumatoid arthritis measured by digital X-ray radiogrammetry predicts radiographic joint damage after one year

  Total Radiographic progression BMD loss
   No Yes p value No Yes p value
Age 58 (14.5) 57.9 (14.4) 60.3 (14.7) 0.41 55.7 (15.5) 60.3 (13.4) 0.042
Women, n (%) 107 (64) 84/135 (62.2) 23/32 (71.9) 0.41 38/69 (55.1) 69/98 (70.4) 0.05
Symptom duration (months) 6 (3.7) 5.5 (3.3) 6.4 (5.0) 0.35 6 (3.2) 5.5 (3.9) 0.31
Anti-CCP2 positive, n (%) 107 (64) 88/135 (65.2) 19/32 (59.4) 0.54 42/69 (60.8) 65/98 (66.3) 0.51
RF positive, n (%) 103 (63) 83/131 (63.4) 20/32 (62.5) 1.0 40/68 (58.8) 63/95 (66.3) 0.41
ESR (mm/h) 29 (21.4) 27.3 (21.1) 35.4 (21.8) 0.055 25.4 (18.2) 31.3 (23.2) 0.066
CRP (mg/ml) 22 (24.4) 21.6 (25.0) 24.7 (22.2) 0.51 18.2 (23) 25 (25.1) 0.074
DAS 28 4.86 (1.30) 4.79 (1.3) 5.12 (1.4) 0.21 4.57 (1.27) 5.06 (1.29) 0.023
HAQ 0.94 (0.60) 0.91 (0.59) 1.08 (0.59) 0.15 0.86 (0.55) 1 (0.62) 0.16
Larsen total 4.1 (4.9) 3.57 (4.63) 6.25 (5.46) 0.005 3.16 ((4.23) 4.73 (5.24) 0.034
DXR-BMD 579.5 (86.1) 584.7 (84.2) 558.0 (91.7) 0.115 600.6 (84.2) 564.8 (84.7) 0.008
DXR-BMD loss 0.68 (1.81) −0.52 (1.65) −1.37 (2.31) 0.058 0.83 (1.05) −1.74 (1.45) < 0.001
  1. Values are mean (SD) unless otherwise stated
  2. Abbreviations: CCP cyclic citrullinated peptides, RF rheumatoid factor, ESR erythrocyte sedimentation rate, CRP C-reactive protein, DAS28 Disease Activity Score, HAQ Health Assessment Questionnaire, DXR-BMD bone mineral density measured by digital X-ray radiogrammetry
  3. p values in italics are statistically significant