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Table 1 Baseline characteristics of patients with active and inactive SLE

From: Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus

Variables

Active SLE (n = 64)

Inactive SLE (n = 54)

p value

Demographic data

 Age, years

33.5 (19.0)

41.5 (20.0)

0.029

 Female sex, n (%)

57 (89.0)

42 (77.7)

0.098

 Disease duration, (months)

1.0 (75.5)

62.5 (177.0)

<0.001

 SLEDAI-2 K

8.0 (5.0)

2.0 (2.0)

<0.001

 New-onset SLE, n (%)

33 (51.5)

5 (9.2)

<0.001

Laboratory data

 WBC count (/μL)

3570.0 (3225.0)

4900.0 (3450.0)

0.006

 Haemoglobin (g/dL)

9.9 (2.5)

13.2 (2.4)

<0.001

 Platelet count (×1000/μL)

158.5 (125.0)

227.0 (111.0)

<0.001

 Lymphocyte count (/μL)

580.0 (461.0)

1260.0 (770.0)

<0.001

 ESR (mm/h)

46.5 (55.0)

19.5 (23.0)

<0.001

 CRP (mg/L)

9.9 (20.3)

0.6 (1.5)

<0.001

 BUN (mg/dL)

13.7 (9.9)

12.8 (5.3)

0.025

 Cr (mg/dL)

0.6 (0.4)

0.6 (0.2)

0.047

 Albumin (mg/dL)

2.9 (1.0)

4.1 (0.5)

<0.001

 AST (IU/L)

30.5 (27.5)

19.5 (7.0)

0.028

 ALT (IU/L)

18.5 (15.5)

16.5 (13.0)

0.036

 Total bilirubin (mg/dL)

0.4 (0.2)

0.5 (0.3)

0.726

 Complement 3, mg/dL

50.4 (41.0)

85.0 (33.6)

<0.001

 Complement 4, mg/dL

8.5 (9.4)

16.4 (9.3)

<0.001

 Anti-dsDNA (IU/mL)

163.5 (360.0)

0.0 (43.0)

<0.001

 Urine P/Cr ratio

0.4 (2.8)

0.0 (0.1)

<0.001

  1. Values are expressed as the median (interquartile range) or number (percentage)
  2. AST aspartate aminotransferase; ALT alanine aminotransferase; BUN blood urea nitrogen; Cr creatinine, CRP C-reactive protein, ESR erythrocyte sedimentation rate, P/Cr protein/creatinine, SLE systemic lupus erythematosus, SLEDAI-2 K Systemic Lupus Erythematosus Disease Activity Index-2000, WBC white blood cell