Table 2 Comparison of IFN-γ releasing assay (IGRA) results in patients with active and inactive SLE
Variables | Active SLE (n = 64) | Inactive SLE (n = 54) | p value |
|---|---|---|---|
IGRA results, n (%) | |||
Positive | 4 (6.2) | 9 (16.6) | 0.073 |
Negative | 31 (48.4) | 45 (83.3) | <0.001 |
Indeterminate | 29 (45.3) | 0 (0.0) | <0.001 |
IFN-γ level (IU/mL) | |||
Nil (IU/mL) | 0.45 (2.00) | 0.09 (0.05) | <0.001 |
Tuberculosis antigen (IU/mL) | 0.43 (1.61) | 0.12 (0.21) | 0.028 |
Mitogen (IU/mL) | 2.93 (7.09) | 11.15 (5.03) | <0.001 |
Ex vivo IFN-γ production (IU/mL)a | 0.92 (4.93) | 11.06 (5.27) | <0.001 |