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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Estrogen attenuates the spondyloarthritis manifestations of the SKG arthritis model

Fig. 2

Quantitative measurement of 18F-fluorodeoxyglucose (18F-FDG) uptake. Visualization of 18F-FDG uptake in the spine of a wild-type (control) mouse and a mouse 8 weeks after zymosan injection (zymosan-treated) (a). Quantification of regions of interest (ROIs) in control, sham-operated (Sham), ovariectomy (OVx), and OVx + 17β-estradiol (OVx + E2) groups. b-g Forepaw (b), hind paw (c), hip joint (d), sacroiliac joint (e), tail (f), total of ROIs of five joints (g), and intestine (h). Values are mean ± SEM, n = 12 mice per group except for the wild-type control group (n = 2); *P < 0.05, **P < 0.01, ***P < 0.001 versus controls. PET/CT positron emission tomography/computed tomography

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