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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production

Fig. 1

Plasma concentrations of IL-12p40, IL-12p70, and IL-23. a Plasma concentrations of IL-12p40 and IL-12p70 were significantly higher in patients (Pt) with Takayasu arteritis (TAK) than in healthy controls (HC) (p < 0.01 and p < 0.01, respectively). b Plasma concentrations of IL-12p40 in patients with TAK were positively correlated with erythrocyte sedimentation rate (ESR) (rho = 0.46, p < 0.01) and C-reactive protein (CRP) (rho = 0.31, p = 0.042). c Plasma concentrations of IL-12p70 were significantly higher in the risk group (AA + AC) than in the non-risk group (CC) (p = 0.012); A adenine, C cytosine. Statistical analysis was performed using a Brunner-Munzel test (a and c) and Spearman’s rank correlation coefficient (b). *p < 0.05 and ** p < 0.01

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