Skip to main content

Advertisement

Table 3 Multivariate analysis of HBV infection status and liver enzyme elevation (Model 3)

From: Assessing risk of liver enzyme elevation in patients with immune-mediated diseases and different hepatitis B virus serostatus receiving anti-TNF agents: a nested case-control study

Patient characteristics (n = 368) OR (95% CI)
HBV infection status HBsAg+ vs uninfected 7.91 (2.16–31.31)
HBsAg/HBcAb+ vs uninfected 1.00 (0.33–3.25)
Sex Female vs male 0.91 (0.34–2.54)
Agea 20-year intervals 0.47 (0.24–0.91)
History of elevated ALT History vs no history 13.71 (4.32–45.75)
Methotrexate Methotrexate + folic acid vs no methotrexate 2.00 (0.61–7.20)
Methotrexate alone without folic acid vs no methotrexate 11.60 (2.52–56.46)
  1. a Age categorised by 20-year intervals; 1 = 0–20 years, 2 = 20–40 years, 3 = 40–60 years, 4 = 60–80 years, 5 = ≥ 80 years
  2. ALT alanine aminotransferase, CI confidence interval, HBcAb + HBV core antibody positive, HBsAg +/ HBV surface antigen positive/negative, HBV hepatitis B virus, OR odds ratio