Characteristic | All patients (N = 339) | Concordant group (n = 236) | Discordant groupa (n = 103) | P value |
---|---|---|---|---|
Age, years | 63.5 (55.1–72.8) | 62.4 (55.1–73.8) | 63.5 (54.9–72.0) | .79 |
Sex | .15 | |||
 Female | 235 (69) | 158 (67) | 77 (75) |  |
 Male | 104 (31) | 78 (33) | 26 (25) |  |
Disease duration, years | 7.0 (2.7, 11.4) | 7.4 (3.5, 11.7) | 6.3 (2.2, 8.8) | .53 |
Provider type | .63 | |||
 NP/PA | 230 (68) | 160 (68) | 70 (68) |  |
 Physician | 90 (27) | 61 (26) | 29 (28) |  |
 Fellow | 19 (6) | 15 (6) | 4 (4) |  |
Comorbidity | ||||
 Fibromyalgia | 28 (8) | 10 (4) | 18 (17) | < .001 |
 Depression | 101 (30) | 61 (26) | 40 (39) | .02 |
 Osteoarthritis | 184 (54) | 121 (51) | 63 (61) | .09 |
 Sleep apnea | 63 (19) | 47 (20) | 16 (16) | .34 |
 Obesity (BMI ≥ 30 kg/m2) | 130 (42) | 87 (39) | 43 (47) | .19 |
 BMI, kg/m2 | 28.5 (25.1–33.7) | 28.4 (24.2–32.9) | 29.4 (26.5–35.4) | .03 |
Disease assessment | ||||
 Patient global, 0-100 | 33 (11–57) | 20 (6–44) | 57 (46–72) | < .001 |
 Provider global, 0-100 | 15 (5–30) | 15 (5–40) | 15 (10–20) | .20 |
 Pain VAS, 0-100 | 38 (15–63) | 24 (9–50) | 60 (44–73) | < .001 |
 Tender joint count ≥ 2 | 121 (36) | 75 (32) | 46 (45) | .02 |
 Swollen joint count ≥ 2 | 122 (36) | 82 (35) | 40 (39) | .47 |
 DAS28-CRP | 3.0 (2.2–4.4) | 2.6 (1.9–4.1) | 3.7 (2.7–4.7) | .004 |
 CDAI | 7.5 (3.0–14.5) | 5.6 (2.0–13.8) | 9.8 (6.5–15.6) | < .001 |
  Remission, < 2.8 | 80 (24) | 78 (33) | 2 (2) | < .001 |
  LDA, ≥ 2.8 to < 10.0 | 130 (38) | 79 (33) | 51 (50) |  |
  MDA, ≥ 10.0 to < 22.0 | 89 (26) | 51 (22) | 38 (37) |  |
  HDA, ≥ 22.0 | 40 (12) | 28 (12) | 12 (12) |  |
Laboratory assessment | ||||
 CRP, mg/L | 3.2 (2.9–9.2) | 3.3 (2.9–9.4) | 3.2 (2.9–9.2) | .96 |
 RF positivity | 233 (71) | 173 (75) | 60 (61) | .01 |
 Anti-CCP antibody positivity | 201 (67) | 146 (71) | 55 (59) | .045 |
Radiographic joint erosion | 172 (52) | 133 (57) | 39 (39) | .002 |
Medication use | ||||
 Prednisone | 150 (44) | 101 (43) | 49 (48) | .42 |
 Methotrexate | 215 (63) | 148 (63) | 67 (65) | .68 |
 Biologics | 125 (37) | 83 (35) | 42 (41) | .33 |
 Change of RA medications at index visit | 91 (27) | 69 (29) | 22 (21) | .13 |
 Opioid | 78 (23) | 45 (19) | 33 (32) | .009 |
 Fibromyalgia med | 33 (10) | 16 (7) | 17 (17) | .005 |
 Sleep aid | 36 (11) | 18 (8) | 18 (17) | .007 |
 Antidepressant or anxiolytic | 80 (24) | 45 (19) | 35 (34) | .003 |