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Table 1 Characteristics of EIRA RA cases and controls

From: Low levels of antibodies against common viruses associate with anti-citrullinated protein antibody-positive rheumatoid arthritis; implications for disease aetiology

  RA cases (n = 990) Controls (n = 700)
Age, years, mean (SD) 50.5 (12.7) 51.5 (11.9)
Gender, female/male (% female) 700/290 (71) 500/200 (71)
ACPA positive (%) 601 (61) N/A
IgM RF positive (%) 653 (66) N/A
DAS28, median (IQR) 5.07 (4.08-5.91) N/A
CRP, mg/l, median (IQR) 16.0 (8.0-31.0) N/A
Smoking status, evera (%) 558 (56) 355 (51)
HLA-DRB1 SE positiveb (%) 711 (72) 342 (49)
  1. aFormer and current cigarette smokers.
  2. bCarriers of one or two HLA-DRB1 SE alleles
  3. ACPA anti-citrullinated protein antibody, RF rheumatoid factor, CRP C-reactive protein, DAS28 disease activity score in 28 joints, IQR interquartile range, N/A not applicable, RA rheumatoid arthritis, SD standard deviation, SE shared epitope