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Table 1 Characteristics of EIRA RA cases and controls

From: Low levels of antibodies against common viruses associate with anti-citrullinated protein antibody-positive rheumatoid arthritis; implications for disease aetiology

 

RA cases (n = 990)

Controls (n = 700)

Age, years, mean (SD)

50.5 (12.7)

51.5 (11.9)

Gender, female/male (% female)

700/290 (71)

500/200 (71)

ACPA positive (%)

601 (61)

N/A

IgM RF positive (%)

653 (66)

N/A

DAS28, median (IQR)

5.07 (4.08-5.91)

N/A

CRP, mg/l, median (IQR)

16.0 (8.0-31.0)

N/A

Smoking status, evera (%)

558 (56)

355 (51)

HLA-DRB1 SE positiveb (%)

711 (72)

342 (49)

  1. aFormer and current cigarette smokers.
  2. bCarriers of one or two HLA-DRB1 SE alleles
  3. ACPA anti-citrullinated protein antibody, RF rheumatoid factor, CRP C-reactive protein, DAS28 disease activity score in 28 joints, IQR interquartile range, N/A not applicable, RA rheumatoid arthritis, SD standard deviation, SE shared epitope