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Table 1 Clinical characteristics and disease activity of patients with and without residual disease activity

From: Residual disease activity and treatment adjustments in psoriatic arthritis in current clinical practice

 

Total group (n = 142)

Residual disease activity according to rheumatologist (n = 90)

No residual disease activity according to rheumatologist (n = 52)

Residual disease vs no residual disease

P value

Age mean (SD)

53.0 (12.6)

53.6 (6.3)

51.9 (13.6)

0.000

Male/female n/n

92/60

53/37

33/19

0.865

Disease duration diagnosis mean (SD)

10.3 (7.9)

11.0 (9.2)

10.1 (6.8)

0.494

on treatment > 6 months, %

93

86

94

0.618

Current only DMARD user n (%)

110 (49)

52 (58)

23 (44)

0.032

Current first TNF user n (%)

32 (22)

14 (16)

18 (35)

 

Current > 1 TNF user n (%)

35 (24)

24 (27)

11 (21)

 

Swollen joints

0 (0–0)

0 (0–1)

0 (0–0)

0.000

SJC of 0, n (%)

111 (77)

63 (70)

49 (94)

SJC of 1, n (%)

10 (7)

8 (9)

2 (4)

SJC of 2, n (%)

5 (3)

5 (6)

0 (0)

SJC of ≥ 3, n (%)

15 (10)

14 (16)

1 (2)

Tender joints

1 (0–2)

1 (0–3)

0 (0–0)

0.000

TJC of 0, n (%)

82 (57)

36 (40)

46 (88)

TJC of 1, n (%)

21 (13)

16 (18)

5 (10)

TJC of 2, n (%)

12 (13)

12 (13)

0 (-)

TJC of 3, n (%)

25 (17)

24 (27)

1 (2)

Number of dactylitic digits

0 (0–0)

0 (0–0)

0 (0–0)

0.017

Dactylitis count of 1, n (%)

8 (6)

8 (9)

0 (-)

Number of enthesitis points

0 (0–0)

0 (0–0)

0 (0–0)

0.001

Enthesitis count of 1, n (%)

14 (10)

14 (16)

0 (-)

Enthesitis count of 2–4, n (%)

2 (1)

2 (2)

0 (-)

VAS physician skin severity

1 (0–2)

1 (1–2.5)

1 (0–1)

0.000

VAS physician overall disease activity

1 (1–3)

2 (1–4)

1 (0–1)

0.000

VAS patient global disease activity

2 (1–6)

5 (2–7)

1 (0–2)

0.000

VAS pt pain

2 (1–6)

5 (2–7)

1 (0–2)

0.000

BASDAI

2,65 (1–4.8)

4.1 (2.5–5.9)

0.9 (0.4–1.8)

0.000

cDAPSA remission, n (%)

45 (32)

9 (10)

36 (69)

0.000

cDAPSA low disease activity, n (%)

49 (35)

34 (38)

15 (29)

 

cDAPSA moderate disease activity, n (%)

35 (25)

35 (39)

0 (-)

 

cDAPSA high disease activity, n (%)

6 (4)

6 (7)

0 (-)

 

cDAPSA missing, n (%)

7 (5)

6 (7)

1 (2)

 
  1. Values are median (IQR) unless stated otherwise. Significance of the comparisons was determined by independent sample t test for continuous variables and the Mann-Whitney U test for non-normally distributed variables. The comparisons within cDAPSA groups were determined by the Kruskall-Wallis test
  2. csDMARD conventional synthetic disease-modifying anti-rheumatic drugs, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, TNFi tumor necrosis factor inhibitor, SJC swollen joint count, TJC tender joint count, VAS visual analog scale, cDAPSA clinical Disease Activity in PsA score