Table 4 Multivariable analysis of relationship of incretins and dipeptidyl peptidase 4 with insulin resistance indexes
β Coefficient (95% CI) | β Coefficient (95% CI) | |||||
|---|---|---|---|---|---|---|
HOMA-IR | p Value | p Value* | HOMA2%B-C-peptide | p Value | p Value* | |
GLP-1, ng/ml | ||||||
Patients with RA | 0.00 (−0.93 to 0.93) | 0.99 | 0.068 | 155 (105 to 205) | 0.000 | 0.003 |
Control subjects | −1.34 (−2.46 to −0.23) | 0.018 | 37 (−22 to 96) | 0.22 | ||
GIP, ng/ml | ||||||
Patients with RA | 0.32 (0.10 to 0.53) | 0.004 | 0.42 | 59 (50 to 68) | 0.000 | 0.29 |
Control subjects | 0.14 (−0.22 to 0.51) | 0.44 | 49 (31 to 66) | 0.000 | ||
DPP-4, ng/ml | ||||||
Patients with RA | −0.002 (−0.003 to −0.002) | 0.000 | 0.39 | −0.12 (−0.16 to −0.09) | 0.000 | 0.71 |
Control subjects | −0.003 (−0.003 to −0.002) | 0.000 | −0.13 (−0.18 to 0.09) | 0.000 | ||