| |
Univariate analysis
|
Multivariate analysis
|
|---|
|
Parameter
|
Periaortitis/periarteritis (+)
|
Periaortitis/periarteritis (–)
|
p value
|
OR (95% CI)
|
p value
|
|---|
|
Total
|
65
|
114
| | | |
|
Onset age of IgG4-RD (median years)
|
69
|
65
|
0.0075
|
1.04 (1.00–1.08)
|
0.082
|
|
Sex (male/female)
|
53/12
|
78/36
|
0.057
| | |
|
Median number of other organ involvements
|
3
|
3
|
0.63
| | |
|
Allergy (+/–)
|
17/47
|
46/64
|
0.044
|
0.49 (0.23–1.05)
|
0.065
|
|
Smoking (+/–)
|
36/28
|
58/47
|
0.90
| | |
|
Hypertension (+/–)
|
30/34
|
37/70
|
0.11
| | |
|
Median IgG (mg/dl)
|
2266
|
1854
|
0.00015
|
1.0007 (1.0002–1.001)
|
0.0035
|
|
Median IgG4 (mg/dl)
|
511
|
376
|
0.012
| | |
|
Median IgE (IU/ml)
|
172
|
100
|
0.12
| | |
|
Median WBC (/μl)
|
6190
|
6090
|
0.87
| | |
|
Median CRP (mg/dl)
|
0.17
|
0.13
|
0.68
| | |
|
Median RF (U/ml)
|
7
|
6
|
0.73
| | |
|
Median CIC (μg/ml)
|
5.3
|
4.8
|
0.042
|
0.96 (0.88–1.04)
|
0.29
|
|
Median sIL-2R (U/ml)
|
885
|
659
|
0.00049
|
1.0004 (1.00–1.001)
|
0.23
|
- The onset age of IgG4-RD was significantly higher in the positive group. Laboratory tests revealed significant disease activity marker increases in the positive group for IgG, IgG4, CIC, and sIL2R. IgG remained significantly higher in the positive group according to multiple logistic analysis
-
OR odds ratio, CI confidence interval, CIC circulating immune complex, CRP C-reactive protein, IgE immunoglobulin E, IgG immunoglobulin G, IgG4-RD immunoglobulin G4-related disease, RF rheumatoid factor, sIL-2R soluble interleukin-2 receptor, WBC white blood cells
