Skip to main content

Table 2 Comparison of clinical findings between patients with and without IgG4-related periaortitis/periarteritis

From: Clinical features of IgG4-related periaortitis/periarteritis based on the analysis of 179 patients with IgG4-related disease: a case–control study

  Univariate analysis Multivariate analysis
Parameter Periaortitis/periarteritis (+) Periaortitis/periarteritis (–) p value OR (95% CI) p value
Total 65 114    
Onset age of IgG4-RD (median years) 69 65 0.0075 1.04 (1.00–1.08) 0.082
Sex (male/female) 53/12 78/36 0.057   
Median number of other organ involvements 3 3 0.63   
Allergy (+/–) 17/47 46/64 0.044 0.49 (0.23–1.05) 0.065
Smoking (+/–) 36/28 58/47 0.90   
Hypertension (+/–) 30/34 37/70 0.11   
Median IgG (mg/dl) 2266 1854 0.00015 1.0007 (1.0002–1.001) 0.0035
Median IgG4 (mg/dl) 511 376 0.012   
Median IgE (IU/ml) 172 100 0.12   
Median WBC (/μl) 6190 6090 0.87   
Median CRP (mg/dl) 0.17 0.13 0.68   
Median RF (U/ml) 7 6 0.73   
Median CIC (μg/ml) 5.3 4.8 0.042 0.96 (0.88–1.04) 0.29
Median sIL-2R (U/ml) 885 659 0.00049 1.0004 (1.00–1.001) 0.23
  1. The onset age of IgG4-RD was significantly higher in the positive group. Laboratory tests revealed significant disease activity marker increases in the positive group for IgG, IgG4, CIC, and sIL2R. IgG remained significantly higher in the positive group according to multiple logistic analysis
  2. OR odds ratio, CI confidence interval, CIC circulating immune complex, CRP C-reactive protein, IgE immunoglobulin E, IgG immunoglobulin G, IgG4-RD immunoglobulin G4-related disease, RF rheumatoid factor, sIL-2R soluble interleukin-2 receptor, WBC white blood cells