Table 3 Allelic association of SNPs in the replication phase
From: Behçet’s disease risk association fine-mapped on the IL23R–IL12RB2 intergenic region in Koreans
Locus | SNP | BD cases, risk allele/total (%) | Controls, risk allele/total (%) | Allelic association | |
|---|---|---|---|---|---|
OR (95% CI) | P | ||||
IL23R–IL12RB2 | rs1495965 (C > T) | 106/168 (63) | 272/566 (48) | 1.9 (1.3, 2.6) | 0.00062 |
rs1495966 (T > C) | 106/168 (63) | 264/548 (48) | 1.8 (1.3, 2.6) | 0.00071 | |
rs4655535 (G > T) | 107/168 (64) | 277/566 (49) | 1.8 (1.3, 2.6) | 0.00078 | |
rs924080 (T > C) | 143/168 (85) | 413/566 (73) | 2.1 (1.3, 3.4) | 0.0013 | |
rs1966176 (G > A) | 118/168 (70) | 322/562 (57) | 1.8 (1.2, 2.6) | 0.0026 | |
rs6677188 (T > A) | 142/168 (85) | 419/566 (74) | 1.9 (1.2, 3.0) | 0.0049 | |
rs6665569 (T > C) | 103/168 (61) | 271/550 (49) | 1.6 (1.2, 2.3) | 0.0063 | |
IL10 | rs1518111 (A > G) | 120/168 (71) | 408/566 (72) | 1.0 (0.7, 1.4) | 0.87 |
rs1800872 (A > C) | 120/168 (71) | 408/566 (72) | 1.0 (0.7, 1.4) | 0.87 | |
rs1554286 (T > C) | 120/168 (71) | 396/554 (71) | 1.0 (0.7, 1.5) | 0.99 | |