Fig. 5

Interferon-α (IFN-α) enhanced imiquimod-induced IFN-α production and suppressed CpG-induced IFN-α production of plasmacytoid dendritic cells (pDCs). Imiquimod or CpG-induced IFN-α-producing capacity of pDCs pretreated with IFN-α was evaluated by intracellular cytokine staining. Values in graphs indicate percentages of IFN-α⁺ pDCs. Representative data of the IFN-α staining profile of pDCs from three independent experiments are shown. No treat = no treatment