From: Predictive biological markers of systemic lupus erythematosus flares: a systematic literature review
Number of patients (n) | Findings | Study |
---|---|---|
68 | For renal flares: sensitivity 71%, specificity 92%, PPV 50%, NPV 97% | Siegert et al., 1993 [40] |
151 | 10 of 14 patients who developed proliferative nephritis had significant increases in anti-C1q level | Coremans et al., 1995 [15] |
151 | NPV 100% for nephritis | Marto et al., 2005 [39] |
70 | For severe lupus nephritis: sensitivity 100%, specificity 95.7%, PPV 50%, NPV 100% | Meyer et al., 2009 [30] |
23 | For renal flares: sensitivity 75.7%, specificity 84%, PPV 56%, NPV 70% | Matrat et al., 2011 [29] |