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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Soluble CD40L is associated with increased oxidative burst and neutrophil extracellular trap release in Behçet’s disease

Fig. 3

Plasma from patients with Behçet’s disease (BD) stimulates phagocyte oxidative burst activity. Superoxide (a and c) and hydrogen peroxide (b and d) production by neutrophils (a and b) and peripheral blood mononuclear cells (PBMCs) (c and d) from healthy control subjects (HCs; n = 30), patients with active Behçet’s disease (aBD; n = 30), and patients with inactive Behçet’s disease (iBD; n = 31) after human plasma or phorbol 12-myristate 13-acetate stimuli, calculated by the AUC. In general, BD plasma exerted a strong stimulus to oxidative burst by phagocytes from HCs, patients with iBD, and patients with aBD. Bars represent mean ± SE. Statistical analysis was performed by one-way analysis of variance with the Bonferroni posttest

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