Ultrasound verified inflammation and structural damage in patients with hereditary haemochromatosis-related arthropathy

Table 3 Scoring of ultrasound abnormalities according to joint region

	HH-WA	HH-A	HOA
Erosion score
MCP	0 (0–5)	0 (0–7)	0 (0–7)
PIP	0 (0–1)	0 (0–2)	0 (0–4)
DIP	0	0	0 (0–4)
Osteophyte score
MCP	4.5 (0–25)	12.5 (0–30)** ^¥¥	5 (0–18)
PIP	5 (0–16) ^¥¥¥	10 (0–28)^¥	14 (2–30)
DIP	7.5 (0–13) ^¥¥¥	8 (1–17)^¥¥¥	16 (2–24)
Hip	2 (0–5) ^¥¥¥	1 (0–6)^¥¥¥	0 (0–4)
Knee	1.5 (0–5)	2 (0–6)	1 (0–6)
Grey scale synovitis score
MCP	2 (0–12) ^¥¥	3 (0–13)^¥¥¥	1 (0–5)
PIP	1 (0–12) ^¥¥	1.5 (0–12)	4 (0–16)
DIP	0 (0–5) ^¥¥¥	1 (0–6)^¥¥¥	5 (0–14)
Wrist	1 (0–4)	2 (0–4)* ^¥¥	0 (0–4)
Hip	0 (0–1)	0 (0–2)	0 (0–1)
Knee	0 (0–2)	0 (0–5)	0 (0–2)
Ankle	0 (0–3)	0 (0–2)	0 (0–1)
Power Doppler synovitis score
MCP	0 (0–5)	1.5 (0–11)** ^¥¥¥	0 (0–2)
PIP	0 (0–3)	0 (0–6)	0 (0–9)
DIP	0 (0–2)	0 (0–1)	0 (0–5)
Wrist	0 (0–2)	1 (0–5)	0 (0–4)
Hip	0 (0–1)	0	0
Knee	0 (0–1)	0 (0–4)	0 (0–1)
Ankle	0 (0–2)	0 (0–3)	0
Grey scale tenosynovitis score
MCP	0 (0–2)	0 (0–1)	0 (0–3)
PIP	0 (0–5)	0 (0–4)	0 (0–1)
DIP	0	0	0 (0–1)
Wrist	0 (0–2)	0 (0–1)	0 (0–1)
Ankle	0	0	0
Power Doppler tenosynovitis score
MCP	0	0	0 (0–3)
PIP	0	0 (0–3)	0 (0–3)
DIP	0	0	0
Wrist	0	0	0 (0–2)
Ankle	0	0	0

Data indicate the median ultrasound score (range)
HH-A hereditary haemochromatosis with arthropathy, HH-WA hereditary haemochromatosis without arthropathy, HOA hand osteoarthritis, MCP metacarpophalangeal joints, PIP proximal interphalangeal joints, DIP distal interphalangeal joints
*p < 0.05 and **p ≤ 0.01 compared to HH-WA, ^¥ p < 0.05, ^¥¥ p ≤ 0.01 and ^¥¥¥ p ≤ 0.001 compared to HOA; p values are not adjusted for multiple testing

ISSN: 1478-6362