Table 2 Presenting clinical and laboratory features
From: Childhood Takayasu arteritis: disease course and response to therapy
Presenting features | Patients (N = 27) | |
|---|---|---|
Symptoms: | Â | Â |
 Constitutional: | Malaise | 13 (48) |
Weight loss | 8 (30) | |
Fever (> 38.0 C) | 5 (19) | |
Lymphadenopathy | 3 (11) | |
 Cardiovascular: | Claudication of the extremities | 6 (22) |
 Neurological: | Headache | 9 (33) |
Dizziness | 5 (19) | |
Stroke/TIA | 3 (11) | |
Syncope | 3 (11) | |
 Gastrointestinal: | Chronic nausea/vomiting | 5 (19) |
Nonspecific abdominal pain | 4 (15) | |
 Pulmonary: | Shortness of breath | 4 (15) |
Chest pain | 3 (11) | |
 Musculoskeletal: | Back pain | 5 (19) |
 Ocular: | Blurred vision/uveitis/retinal hemorrhage | 4 (15) |
Findings on clinical exam: | ||
| Â | Blood pressure discrepancy | 18 (67) |
Decreased or absent pulse | 16 (59) | |
Arterial hypertension | 15 (56) | |
Bruits over large arteries | 15 (56) | |
Laboratory characteristics: | ||
|  | ESR, mm/h | 35 (17–74) |
CRP, mg/dL | 31.9 (5.3–67.6) | |
Hemoglobin, g/L | 115 (96.5–125.5) | |
White blood cells, × 10^9/L | 8.8 (6.9–12.4) | |
Platelets, × 10^9/L | 366 (256–543) | |
vWF antigen, IU/mL | 1.6 (1.1–2.0) | |
Impaired renal function | 2 (7) | |
ANA | 8/22 (36) | |
ANCA | 2/18 (11) | |