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Table 2 Presenting clinical and laboratory features

From: Childhood Takayasu arteritis: disease course and response to therapy

Presenting features Patients (N = 27)
Symptoms:   
 Constitutional: Malaise 13 (48)
Weight loss 8 (30)
Fever (> 38.0 C) 5 (19)
Lymphadenopathy 3 (11)
 Cardiovascular: Claudication of the extremities 6 (22)
 Neurological: Headache 9 (33)
Dizziness 5 (19)
Stroke/TIA 3 (11)
Syncope 3 (11)
 Gastrointestinal: Chronic nausea/vomiting 5 (19)
Nonspecific abdominal pain 4 (15)
 Pulmonary: Shortness of breath 4 (15)
Chest pain 3 (11)
 Musculoskeletal: Back pain 5 (19)
 Ocular: Blurred vision/uveitis/retinal hemorrhage 4 (15)
Findings on clinical exam:
  Blood pressure discrepancy 18 (67)
Decreased or absent pulse 16 (59)
Arterial hypertension 15 (56)
Bruits over large arteries 15 (56)
Laboratory characteristics:
  ESR, mm/h 35 (17–74)
CRP, mg/dL 31.9 (5.3–67.6)
Hemoglobin, g/L 115 (96.5–125.5)
White blood cells, × 10^9/L 8.8 (6.9–12.4)
Platelets, × 10^9/L 366 (256–543)
vWF antigen, IU/mL 1.6 (1.1–2.0)
Impaired renal function 2 (7)
ANA 8/22 (36)
ANCA 2/18 (11)
  1. Clinical features present in > 10% of the patients with childhood TAK are listed. Impaired renal function was defined as a creatinine increase of > 30% of the upper normal limit at diagnosis. Values are presented as numbers (%) or medians (IQR)
  2. TIA transient ischemic attack, ESR erythrocyte sedimentation rate, CRP C-reactive protein, vWF antigen von Willebrand factor antigen. ANA antinuclear antibody, ANCA antineutrophil cytoplasmic antibody