Fig. 1
From: New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis
Regulatory network of MMP-13 in OA chondrocytes. In the illustration, the dotted lines indicate an indirect effect on MMP-13 and the solid lines indicate a direct effect on a downstream target. Green lines indicate promotion and red lines inhibition of MMP-13. The yellow background indicates increasing expression level and the gray background decreasing expression level in OA chondrocytes