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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

Fig. 3

Expression of microRNA (miR) miR-103a-3p in whole blood or peripheral blood mononuclear cells obtained from healthy control subjects (HCs), patients with rheumatoid arthritis (RA), or first-degree relatives (FDRs). miR-103a-3p transcriptional abundance was analyzed by qPCR. a Scatterplot of normalized cycle threshold (ΔC t) values and fold change of miR-103a-3p relative expression in whole blood of HCs (open circles), patients with RA (filled squares), and FDRs (open triangles). Error bars represent median values analyzed by Kruskal-Wallis test with Dunn’s test for multiple comparisons (*** P < 0.001 vs HCs). b Scatterplot of normalized ΔC t values showing miR-103a-3p expression in whole blood of HCs (open circles) and FDRs (open triangles) collected at two independent time points ~ 1 year apart (T1 and T2)

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