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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

Fig. 4

Transcript abundance of microRNA (miR) miR-103a-3p target messenger RNAs (DICER1, AGO1, CREB1, TP53, and DAPK1) analyzed by qPCR using total RNA obtained from whole blood of healthy control subjects (HCs), patients with rheumatoid arthritis (RA) and first-degree relatives (FDRs). Scatterplots represent relative fold change expression values compared with HCs. Error bars represent median values analyzed by Mann-Whitney U test. ***P < 0.001, ** P < 0.01, *P < 0.05. ns Nonsignificant compared with HCs

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