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Table 1 Clinical characteristics of the study population

From: Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

  Healthy control subjects (n = 12) ACPA+/patients with RA (n = 18) ACPA+/FDRs (n = 12)
Age, years, median (range) 40 (23–66) 46.6 (29–70) 33.65 (28–60)
Sex, female/male 10/2 14/4 12/1
Disease duration, years, median (range) NA 12.02 (0–35.6) NA
CRP titer, median (range) 3.35 (1.07 –9.25) 6.91 (2–42.6) 2.595 (1.01–15.9)
RF titer, IU/ml, median (range)ml <20 321 (20–1540) 34.9 (20–570)
Anti-CCP titer, median (range) 1 (0.4–2.0) 201 (19–289) 114 (7–365)
BMI, kg/m2, median (range) 29.54 (19.9–34.4) 27.37 (20.4–39.6) 26.09 (19.6–40.7)
  1. Abbreviations: ACPA Anticitrullinated protein antibodies, BMI Body mass index, Anti-CCP Anticyclic citrullinated protein antibodies, CRP C-reactive protein, FDR First-degree relative, RA Rheumatoid arthritis, RF Rheumatoid factor, NA Not applicable
  2. All values are reported as median (range) unless otherwise indicated