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Table 1 Clinical characteristics of the study population

From: Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

 

Healthy control subjects (n = 12)

ACPA+/patients with RA (n = 18)

ACPA+/FDRs (n = 12)

Age, years, median (range)

40 (23–66)

46.6 (29–70)

33.65 (28–60)

Sex, female/male

10/2

14/4

12/1

Disease duration, years, median (range)

NA

12.02 (0–35.6)

NA

CRP titer, median (range)

3.35 (1.07 –9.25)

6.91 (2–42.6)

2.595 (1.01–15.9)

RF titer, IU/ml, median (range)ml

<20

321 (20–1540)

34.9 (20–570)

Anti-CCP titer, median (range)

1 (0.4–2.0)

201 (19–289)

114 (7–365)

BMI, kg/m2, median (range)

29.54 (19.9–34.4)

27.37 (20.4–39.6)

26.09 (19.6–40.7)

  1. Abbreviations: ACPA Anticitrullinated protein antibodies, BMI Body mass index, Anti-CCP Anticyclic citrullinated protein antibodies, CRP C-reactive protein, FDR First-degree relative, RA Rheumatoid arthritis, RF Rheumatoid factor, NA Not applicable
  2. All values are reported as median (range) unless otherwise indicated