Skip to main content

Advertisement

Table 1 Demographic and clinical characteristics of participants in two cohorts

From: Serum connective tissue growth factor is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis

  Training cohort Validation cohort
RA (before 1 May 2016) Control (before 1 May 2016) RA (after 16 May 2016) non-RA (after 16 May 2016)
Sex (female/male), n 80/18 50/53 174/43 187/168
Age (years) 58 (27, 85) 49 (19, 86) 59 (15, 84) 48 (13, 94)
Symptom duration (years) 10 (0.01, 50) NA 5 (0.01, 50) 4 (0.01, 50)
CRP (mg/L) 22 (0.6, 331) NA 18.6 (0.16, 339) 8.0 (0.16, 436)
ESR (mm/h) 44 (2, 140) NA 42 (2, 134) 24 (2, 120)
ACPA positive, n (%) 71 (72) NA 147(68) 12 (3)
RF positive, n (%) 65 (66) NA 136 (63) 63 (18)
Serum CTGF (pg/mL) 293.9 (7.87, 1285) 30 (0.16, 171.3) 289.2 (1.82, 2351) 22.45 (0.12, 541)
Synovial fluid CTGF (pg/mL) 534 (1.55, 2574) 23.87 (2.65, 166.8) NA NA
  1. Values are expressed as median (minimum, maximum) unless state otherwise
  2. Abbreviations: RA rheumatoid arthritis, NA not applicable, CRP C-reactive protein, ESR erythrocyte sedimentation rate, ACPA antibodies directed against citrullinated peptides, RF rheumatoid factor, CTGF connective tissue growth factor