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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: The role of aberrant expression of T cell miRNAs affected by TNF-α in the immunopathogenesis of rheumatoid arthritis

Fig. 5

Effect of miR-214 on ERK and JNK protein phosphorylation in Jurkat cells. a The phosphorylation ratio of ERK and JNK increased in Jurkat cells after being cultured with TNF-α (20 ng/mL) for 48 h compared with those cultured with medium (CM) alone and (b) a representative case. c In Jurkat cells after transfection with miR-214 mimic or scramble oligonucleotides cultured with medium alone for 48 h, the phosphorylation ratio of ERK and JNK decreased in those transfected with miR-214 mimic compared with the control groups and (d) a representative case. e In Jurkat cells after transfection with miR-214 mimic or scramble oligonucleotides cultured with TNF-α (20 ng/mL) for 48 h, the phosphorylation ratio of ERK and JNK decreased in those transfected with miR-214 mimic compared with the control groups and (f) a representative case

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