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Table 6 Comparison of laboratory findings and percentage of cases with single organ involvement between the present study and previous reports

From: New clues to the nature of immunoglobulin G4-related disease: a retrospective Japanese multicenter study of baseline clinical features of 334 cases

 

Present study

Inoue et al. [10]

Lin et al. [11]

Campochiaro et al. [22]

Ebbo et al. [23]

Fernández-Codina et al. [24]

Wallace et al. [9]

Reported year

 

2015

2015

2015

2012

2015

2015

Number of patients

334

235

118

41

25

55

125

Country

Japan

Japan

China

Italy

France

Spain

USA

Mean serum IgG level (mg/dl)

2403

NA

2300

NA

2550

NA

1573d, 1130e

Mean serum IgG4 level (mg/dl)

755

470a

1522

284a

720

223a,b, 93a,c

379d, 51e

Elevation of IgG4 (%)

95.5

88

97.5

73

100

NA

51.4

Median serum CRP level (mg/dl)

0.10

NA

NA

0.8

NA

NA

0.55d, 0.65e

Mean serum CRP level (mg/dl)

0.42

NA

0.66

NA

3.09

NA

NA

CRP < 0.5 mg/dl (%)

79.9

NA

NA

NA

NA

NA

NA

CRP < 1.0 mg/dl (%)

90.2

NA

NA

NA

46

NA

NA

Elevation of CRP (%)

27.4

NA

44.1

63

56

NA

67d,f, 46e,f

Single organ involvement (%)

11.4

42

4.2

58.5

12.0

52.7

38

  1. CRP C-reactive protein, IgG4 immunoglobulin G4, IgG4-RD immunoglobulin G4-related disease, NA not applicable
  2. aMedian value
  3. bHighly suggestive IgG4-RD
  4. cProbable IgG4-RD
  5. dPatients with elevated serum IgG4 concentration
  6. ePatients with normal serum IgG4 concentration
  7. fErythrocyte sedimentation rate and/or CRP