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Table 6 Comparison of laboratory findings and percentage of cases with single organ involvement between the present study and previous reports

From: New clues to the nature of immunoglobulin G4-related disease: a retrospective Japanese multicenter study of baseline clinical features of 334 cases

  Present study Inoue et al. [10] Lin et al. [11] Campochiaro et al. [22] Ebbo et al. [23] Fernández-Codina et al. [24] Wallace et al. [9]
Reported year   2015 2015 2015 2012 2015 2015
Number of patients 334 235 118 41 25 55 125
Country Japan Japan China Italy France Spain USA
Mean serum IgG level (mg/dl) 2403 NA 2300 NA 2550 NA 1573d, 1130e
Mean serum IgG4 level (mg/dl) 755 470a 1522 284a 720 223a,b, 93a,c 379d, 51e
Elevation of IgG4 (%) 95.5 88 97.5 73 100 NA 51.4
Median serum CRP level (mg/dl) 0.10 NA NA 0.8 NA NA 0.55d, 0.65e
Mean serum CRP level (mg/dl) 0.42 NA 0.66 NA 3.09 NA NA
CRP < 0.5 mg/dl (%) 79.9 NA NA NA NA NA NA
CRP < 1.0 mg/dl (%) 90.2 NA NA NA 46 NA NA
Elevation of CRP (%) 27.4 NA 44.1 63 56 NA 67d,f, 46e,f
Single organ involvement (%) 11.4 42 4.2 58.5 12.0 52.7 38
  1. CRP C-reactive protein, IgG4 immunoglobulin G4, IgG4-RD immunoglobulin G4-related disease, NA not applicable
  2. aMedian value
  3. bHighly suggestive IgG4-RD
  4. cProbable IgG4-RD
  5. dPatients with elevated serum IgG4 concentration
  6. ePatients with normal serum IgG4 concentration
  7. fErythrocyte sedimentation rate and/or CRP