Table 3 Biomarker levels of patients in the progression and non-progression groups at ACL reconstruction (baseline)
Variables | Total (n = 62) | Progression group (n = 15) | Non-progression group (n = 47) | p value | |
|---|---|---|---|---|---|
C2C (ng/ml) | Median (IQR) | 9.8 (5.8–13.8) | 8.8 (5.6–11.8) | 10.4 (6.1–14.3) | 0.282 |
Δdi-C6S (nmol/ml) | Median (IQR) | 69.6 (54.9–95.1) | 53.4 (50.9–69.4) | 73.5 (60.7–99.9) | 0.004 |
Δdi-C4S (nmol/ml) | Median (IQR) | 17.1 (14.2–21.6) | 16.3 (14.8–17.8) | 18.0 (14.2–23.0) | 0.170 |
KS (μg/ml) | Median (IQR) | 11.6 (9.4–15.6) | 9.9 (8.3–11.4) | 11.9 (10.0–16.0) | 0.021 |
C2C/KS ratio | Median (IQR) | 0.71 (0.51–1.2) | 0.67 (0.52–1.2) | 0.75 (0.51–1.2) | 0.928 |
C6S/C4S ratio | Median (IQR) | 4.2 (3.6–4.9) | 3.9 (3.2–4.4) | 4.4 (3.7–5.2) | 0.028 |