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Table 1 Increased gene expression by resistin-stimulated RA FLSs

From: Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

Gene Description Fold change (resistin/not stimulated) RPKM Ensembl gene ID
Lot 1 Lot 2 Lot 3
Lot 1 Lot 2 Lot 3 Mean Non RS Non RS Non RS
CXCL5 C-X-C motif chemokine ligand 5 3.51 31.88 3.40 12.93 0.088 0.310 0.151 4.822 0.245 0.832 ENSG00000163735
CXCL6 C-X-C motif chemokine ligand 6 7.76 20.32 3.76 10.61 0.205 1.594 0.106 2.144 0.821 3.089 ENSG00000124875
IL34 Interleukin 34 17.56 5.63 2.37 8.52 0.033 0.588 0.172 0.967 0.309 0.732 ENSG00000157368
CXCL1 C-X-C motif chemokine ligand 1 3.13 18.39 3.63 8.39 2.538 7.952 1.066 19.609 3.991 14.506 ENSG00000163739
CXCL8 C-X-C motif chemokine ligand 8 5.07 10.25 4.21 6.51 0.592 3.002 1.384 14.183 1.152 4.853 ENSG00000169429
BIRC3 Baculoviral IAP repeat containing 3 3.44 7.06 6.42 5.64 0.230 0.789 0.195 1.376 0.129 0.828 ENSG00000023445
IL1B Interleukin 1 beta 2.20 10.47 4.12 5.59 0.097 0.212 0.149 1.558 0.134 0.550 ENSG00000125538
AFP Alpha fetoprotein 4.39 6.56 2.57 4.51 0.023 0.101 0.024 0.155 0.106 0.272 ENSG00000081051
SOD2 Superoxide dismutase 2 3.27 5.33 3.63 4.08 4.587 15.002 4.327 23.048 5.692 20.663 ENSG00000112096
CCL2 C-C motif chemokine ligand 2 2.31 5.80 2.89 3.66 20.170 46.526 23.381 135.522 16.826 48.585 ENSG00000108691
ANXA8L1 Annexin A8 like 1 2.63 3.19 4.94 3.59 0.035 0.093 0.180 0.575 0.032 0.160 ENSG00000264230
SLC5A2 Solute carrier family 5 member 2 3.51 2.11 4.94 3.52 0.017 0.059 0.069 0.145 0.015 0.076 ENSG00000140675
CXCL3 C-X-C motif chemokine ligand 3 3.95 3.09 2.63 3.23 0.270 1.065 0.346 1.071 0.466 1.228 ENSG00000163734
ZNF296 Zinc finger protein 296 2.05 3.75 2.96 2.92 0.129 0.263 0.088 0.330 0.119 0.352 ENSG00000170684
ICAM1 Intercellular adhesion molecule 1 2.29 3.56 2.43 2.76 2.380 5.455 2.590 9.227 1.935 4.705 ENSG00000090339
IL32 Interleukin 32 3.25 2.33 2.39 2.66 0.690 2.245 3.020 7.042 1.061 2.539 ENSG00000008517
LY75 Lymphocyte antigen 75 2.63 2.81 2.30 2.58 0.016 0.042 0.024 0.069 0.044 0.101 ENSG00000054219
CXCL2 C-X-C motif chemokine ligand 2 2.07 2.29 2.33 2.23 0.698 1.444 0.819 1.872 1.011 2.361 ENSG00000081041
  1. FLSs fibroblast-like synoviocytes, RA rheumatoid arthritis, RPKM reads per kilobase of transcript per million reads mapped, RS resistin-stimulated, Non non-stimulated. FLSs from synovial tissue in RA were incubated with 1000 ng/ml resistin for 18 h. mRNA expression was analyzed by next-generation sequencing. Genes with expression levels that were more than twofold higher in resistin-stimulated FLSs than in unstimulated FLSs are shown