Skip to main content

Table 1 Increased gene expression by resistin-stimulated RA FLSs

From: Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

Gene

Description

Fold change (resistin/not stimulated)

RPKM

Ensembl gene ID

Lot 1

Lot 2

Lot 3

Lot 1

Lot 2

Lot 3

Mean

Non

RS

Non

RS

Non

RS

CXCL5

C-X-C motif chemokine ligand 5

3.51

31.88

3.40

12.93

0.088

0.310

0.151

4.822

0.245

0.832

ENSG00000163735

CXCL6

C-X-C motif chemokine ligand 6

7.76

20.32

3.76

10.61

0.205

1.594

0.106

2.144

0.821

3.089

ENSG00000124875

IL34

Interleukin 34

17.56

5.63

2.37

8.52

0.033

0.588

0.172

0.967

0.309

0.732

ENSG00000157368

CXCL1

C-X-C motif chemokine ligand 1

3.13

18.39

3.63

8.39

2.538

7.952

1.066

19.609

3.991

14.506

ENSG00000163739

CXCL8

C-X-C motif chemokine ligand 8

5.07

10.25

4.21

6.51

0.592

3.002

1.384

14.183

1.152

4.853

ENSG00000169429

BIRC3

Baculoviral IAP repeat containing 3

3.44

7.06

6.42

5.64

0.230

0.789

0.195

1.376

0.129

0.828

ENSG00000023445

IL1B

Interleukin 1 beta

2.20

10.47

4.12

5.59

0.097

0.212

0.149

1.558

0.134

0.550

ENSG00000125538

AFP

Alpha fetoprotein

4.39

6.56

2.57

4.51

0.023

0.101

0.024

0.155

0.106

0.272

ENSG00000081051

SOD2

Superoxide dismutase 2

3.27

5.33

3.63

4.08

4.587

15.002

4.327

23.048

5.692

20.663

ENSG00000112096

CCL2

C-C motif chemokine ligand 2

2.31

5.80

2.89

3.66

20.170

46.526

23.381

135.522

16.826

48.585

ENSG00000108691

ANXA8L1

Annexin A8 like 1

2.63

3.19

4.94

3.59

0.035

0.093

0.180

0.575

0.032

0.160

ENSG00000264230

SLC5A2

Solute carrier family 5 member 2

3.51

2.11

4.94

3.52

0.017

0.059

0.069

0.145

0.015

0.076

ENSG00000140675

CXCL3

C-X-C motif chemokine ligand 3

3.95

3.09

2.63

3.23

0.270

1.065

0.346

1.071

0.466

1.228

ENSG00000163734

ZNF296

Zinc finger protein 296

2.05

3.75

2.96

2.92

0.129

0.263

0.088

0.330

0.119

0.352

ENSG00000170684

ICAM1

Intercellular adhesion molecule 1

2.29

3.56

2.43

2.76

2.380

5.455

2.590

9.227

1.935

4.705

ENSG00000090339

IL32

Interleukin 32

3.25

2.33

2.39

2.66

0.690

2.245

3.020

7.042

1.061

2.539

ENSG00000008517

LY75

Lymphocyte antigen 75

2.63

2.81

2.30

2.58

0.016

0.042

0.024

0.069

0.044

0.101

ENSG00000054219

CXCL2

C-X-C motif chemokine ligand 2

2.07

2.29

2.33

2.23

0.698

1.444

0.819

1.872

1.011

2.361

ENSG00000081041

  1. FLSs fibroblast-like synoviocytes, RA rheumatoid arthritis, RPKM reads per kilobase of transcript per million reads mapped, RS resistin-stimulated, Non non-stimulated. FLSs from synovial tissue in RA were incubated with 1000 ng/ml resistin for 18 h. mRNA expression was analyzed by next-generation sequencing. Genes with expression levels that were more than twofold higher in resistin-stimulated FLSs than in unstimulated FLSs are shown
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us